Advancing AI Literacy Lessons

Cracking the Code: DNA Replication with AI Insights

Biology | 9-12
Duration: 70 minutes
Author: Dr. Vashunda Warren, STEM Teacher and High School Principal

This lesson dives into the intricate process of DNA replication while leveraging AI as a learning partner. Students will engage in a jigsaw activity where AI-generated prompts guide their understanding of replication steps. A whole-class discussion will challenge learners to evaluate the accuracy and limitations of AI explanations. By revising concept maps with AI feedback, students will strengthen their grasp of molecular biology and develop skills to critically assess digital tools.

Lesson Plan Series

Lesson Objectives

Deconstruct the steps of DNA replication during interphase and model why replication is semiconservative.
Evaluate AI explanations of replication for accuracy, completeness, and precision; justify revisions with cited sources.
Formulate high-quality prompts that direct a generative AI system to clarify misconceptions about replication.
Integrate replication into their existing concept map to show how replication supports the continuity of life.

Essential Questions

How does the mechanism of DNA replication preserve continuity of life from one cell generation to the next?
When an AI sounds confident, how can we determine whether it is scientifically correct—and what evidence should drive revision?